Evidence Engine
Contested Claims

Where the literature disagrees

50 relationships in the C. elegans knowledge graph have both supporting and refuting evidence in the published literature. Click any row to see every claim, sorted by direction.

Most-contested relationships

clear — Animals appear unusually transparent when compared to control.positively regulatesWBbt:0004017PhenotypeAnatomy
172 claims154 supports8 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.regulatesWBbt:0004017PhenotypeAnatomy
149 claims135 supports1 refutescontested
WBbt:0004017positively regulatesclear — Animals appear unusually transparent when compared to control.AnatomyPhenotype
113 claims101 supports3 refutescontested
WBbt:0004017positively regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
103 claims83 supports3 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.positively regulatesWBbt:0004017PhenotypeAnatomy
93 claims79 supports3 refutescontested
WBbt:0004017regulatesmolt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.AnatomyPhenotype
81 claims77 supports1 refutescontested
WBbt:0004017regulatesclear — Animals appear unusually transparent when compared to control.AnatomyPhenotype
79 claims71 supports1 refutescontested
WBbt:0004017positively regulatesmolt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.AnatomyPhenotype
83 claims69 supports2 refutescontested
WBbt:0004017positively regulatesthin — Animals exhibit a reduced girth compared to a control animal of the same developmental stage.AnatomyPhenotype
68 claims56 supports7 refutescontested
clear — Animals appear unusually transparent when compared to control.regulatesWBbt:0004017PhenotypeAnatomy
66 claims55 supports2 refutescontested
long — Animals are longer than control animals at the same developmental stage.positively regulatesWBbt:0004017PhenotypeAnatomy
71 claims54 supports3 refutescontested
WBbt:0004017regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
64 claims54 supports1 refutescontested
WBbt:0004017regulatesWBls:0000092AnatomyLifeStage
56 claims53 supports1 refutescontested
WBbt:0004017positively regulatesWBls:0000092AnatomyLifeStage
56 claims52 supports2 refutescontested
WBbt:0003960positively regulatesunfolded protein response variant — Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.AnatomyPhenotype
54 claims50 supports1 refutescontested
long — Animals are longer than control animals at the same developmental stage.positively regulatesWBbt:0003760PhenotypeAnatomy
50 claims43 supports1 refutescontested
small — Animals are shorter and thinner than control animals at the same developmental stage.positively regulatesWBbt:0004017PhenotypeAnatomy
44 claims41 supports1 refutescontested
WBbt:0004017regulatesthin — Animals exhibit a reduced girth compared to a control animal of the same developmental stage.AnatomyPhenotype
42 claims37 supports1 refutescontested
WBGene00000912positively regulatesWBGene00004804ProteinProtein
38 claims33 supports2 refutescontested
WBbt:0003960positively regulatesclear — Animals appear unusually transparent when compared to control.AnatomyPhenotype
34 claims33 supports1 refutescontested
WBbt:0004017positively regulatesWBls:0000023AnatomyLifeStage
40 claims33 supports1 refutescontested
thin — Animals exhibit a reduced girth compared to a control animal of the same developmental stage.positively regulatesWBbt:0004017PhenotypeAnatomy
37 claims33 supports1 refutescontested
WBls:0000023positively regulatesWBls:0000710LifeStageLifeStage
35 claims32 supports1 refutescontested
WBbt:0004017positively regulatesWBls:0000710AnatomyLifeStage
39 claims30 supports3 refutescontested
WBls:0000705negatively regulatesWBls:0000023LifeStageLifeStage
31 claims30 supports1 refutescontested
WBbt:0004017negatively regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
38 claims30 supports1 refutescontested
thin — Animals exhibit a reduced girth compared to a control animal of the same developmental stage.regulatesWBbt:0004017PhenotypeAnatomy
39 claims29 supports1 refutescontested
WBls:0000023positively regulatesWBbt:0004017LifeStageAnatomy
32 claims28 supports1 refutescontested
clear — Animals appear unusually transparent when compared to control.negatively regulatesWBbt:0004017PhenotypeAnatomy
32 claims25 supports4 refutescontested
WBbt:0004017negatively regulatesclear — Animals appear unusually transparent when compared to control.AnatomyPhenotype
34 claims26 supports2 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.causesWBbt:0003760PhenotypeAnatomy
28 claims24 supports2 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.regulatesWBbt:0003960PhenotypeAnatomy
28 claims24 supports1 refutescontested
WBGene00000898regulatesWBGene00000912ProteinProtein
25 claims23 supports2 refutescontested
WBbt:0003760positively regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
29 claims24 supports1 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.negatively regulatesWBbt:0004017PhenotypeAnatomy
27 claims22 supports1 refutescontested
WBbt:0004017required forWBls:0000092AnatomyLifeStage
26 claims21 supports1 refutescontested
WBls:0000710positively regulatesWBls:0000023LifeStageLifeStage
22 claims21 supports1 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.positively regulatesWBbt:0003760PhenotypeAnatomy
24 claims20 supports1 refutescontested
WBbt:0003679positively regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
27 claims20 supports1 refutescontested
molt defect — Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage.regulatesWBbt:0003760PhenotypeAnatomy
25 claims19 supports1 refutescontested
WBls:0000710regulatesWBbt:0007850LifeStageAnatomy
22 claims19 supports1 refutescontested
WBbt:0003679regulateslong — Animals are longer than control animals at the same developmental stage.AnatomyPhenotype
25 claims18 supports1 refutescontested
WBls:0000023expressed inWBls:0000710LifeStageLifeStage
20 claims18 supports1 refutescontested
clear — Animals appear unusually transparent when compared to control.positively regulatesWBGene00000912PhenotypeProtein
24 claims18 supports1 refutescontested
WBbt:0004017causesclear — Animals appear unusually transparent when compared to control.AnatomyPhenotype
20 claims16 supports2 refutescontested
WBbt:0004017regulatesWBls:0000023AnatomyLifeStage
19 claims16 supports2 refutescontested
WBbt:0004017positively regulateshindgut damaged — The terminal portion of the intestine exhibits structural defects such as scarring or blockage.AnatomyPhenotype
20 claims17 supports1 refutescontested
clear — Animals appear unusually transparent when compared to control.positively regulatesWBbt:0003679PhenotypeAnatomy
20 claims16 supports1 refutescontested
WBGene00000912regulatesWBGene00004804ProteinProtein
18 claims16 supports1 refutescontested
small — Animals are shorter and thinner than control animals at the same developmental stage.negatively regulatesWBbt:0004017PhenotypeAnatomy
20 claims15 supports1 refutescontested