Evidence Engine
Gene

dct-15

WBGene00012340protein_coding_geneCaenorhabditis elegans

DAF-16/FOXO Controlled, germline Tumor affecting 15

Synonyms: CELE_W08D2.3, W08D2.3

dct-15 at a glance

Evidence and relationships from published C. elegans research

6Relationships
4Claims

Knowledge Graph Relationships

Outgoing (4)

dct-15enriched inWBbt:0003960Anatomy
1 claims1 supportssupported
dct-15interacts withWBbt:0003960Anatomy
1 claims1 supportssupported
dct-15regulationdct-15Gene
1 claims1 supportssupported
dct-15regulationctc-1Gene
1 claims1 supportssupported

Incoming (2)

WBbt:0005755regulatesdct-15Anatomy
1 claims0 supports
dct-15regulationdct-15Gene
1 claims1 supports

Evidence (4 claims)

Supportsregulation100% conf.
dct-15→COX1

Thus, the results indicated that dct-15 interacted with the mitochondrial DNA polymorphisms in COX1 and is associated with ageing.

Mitochondrial DNA polymorphisms in COX1 affect the lifespan of Caenorhabditis elegans through nuclear gene dct-15.PMID:36063972
Supportsregulation97% conf.
dct-15→dct-15

Moreover, mtDNA variation downregulated the nuclear dct-15 gene expression, which consequently reduced the lifespan, development rate and motility of C. elegans. dct-15 mutations decreased mitochondria copy number but increased ATP content and mitochondrial ultrastructure.

Mitochondrial DNA polymorphisms in COX1 affect the lifespan of Caenorhabditis elegans through nuclear gene dct-15.PMID:36063972
Supportsenriched_in
rial→COX1

Thus, the results indicated that dct-15 interacted with the mitochondrial DNA polymorphisms in COX1 and is associated with ageing.

Mitochondrial DNA polymorphisms in COX1 affect the lifespan of Caenorhabditis elegans through nuclear gene dct-15.PMID:36063972
Supportsinteracts_with
dct-15→rial

Thus, the results indicated that dct-15 interacted with the mitochondrial DNA polymorphisms in COX1 and is associated with ageing.

Mitochondrial DNA polymorphisms in COX1 affect the lifespan of Caenorhabditis elegans through nuclear gene dct-15.PMID:36063972

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